Micro, Nano, and Molecular Systems Article 2019

Recent advances in gold nanoparticles forbiomedical applications: from hybrid structuresto multi-functionality

Au nps

Gold nanoparticles (Au NPs) are arguably the most versatile nanomaterials reported to date. Recentadvances in nanofabrication and chemical synthesis have expanded the scope of Au NPs from classicalhomogeneous nanospheres to a wide range of hybrid nanostructures with programmable size, shapeand composition. Novel physiochemical properties can be achievedviadesign and engineering of thehybrid nanostructures. In this review we discuss the recent progress in the development of complexhybrid Au NPs and propose a classification framework based on three fundamental structuraldimensions (length scale, complexity and symmetry) to aid categorising, comparing and designingvarious types of Au NPs. Their novel functions and potential for biomedical applications will also bediscussed, featuring point-of-care diagnostics by advanced optical spectroscopy and assays, as well asminimally invasive surgeries and targeted drug delivery using multifunctional nano-robot

Author(s): Jeong, H-H and Choi, E. and Ellis, E. and Lee, T.-C.
Journal: J. of Mat. Chem. B
Volume: 7
Pages: 3480
Year: 2019
Month: May
Day: 14
Bibtex Type: Article (article)
DOI: 10.1039/c9tb00557a
URL: https://pubs.rsc.org/en/content/articlepdf/2019/tb/c9tb00557a
Electronic Archiving: grant_archive

BibTex

@article{2019Jeongc,
  title = {Recent advances in gold nanoparticles forbiomedical applications: from hybrid structuresto multi-functionality},
  journal = {J. of Mat. Chem. B},
  abstract = {Gold nanoparticles (Au NPs) are arguably the most versatile nanomaterials reported to date. Recentadvances in nanofabrication and chemical synthesis have expanded the scope of Au NPs from classicalhomogeneous nanospheres to a wide range of hybrid nanostructures with programmable size, shapeand composition. Novel physiochemical properties can be achievedviadesign and engineering of thehybrid nanostructures. In this review we discuss the recent progress in the development of complexhybrid  Au  NPs  and  propose  a  classification  framework  based  on  three  fundamental  structuraldimensions (length scale, complexity and symmetry) to aid categorising, comparing and designingvarious types of Au NPs. Their novel functions and potential for biomedical applications will also bediscussed, featuring point-of-care diagnostics by advanced optical spectroscopy and assays, as well asminimally invasive surgeries and targeted drug delivery using multifunctional nano-robot},
  volume = {7},
  pages = {3480},
  month = may,
  year = {2019},
  slug = {2019jeongc},
  author = {Jeong, H-H and Choi, E. and Ellis, E. and Lee, T.-C.},
  url = {https://pubs.rsc.org/en/content/articlepdf/2019/tb/c9tb00557a},
  month_numeric = {5}
}