Physical Intelligence Conference Paper 2017

Positioning of drug carriers using permanent magnet-based robotic system in three-dimensional space

Publications toc

Magnetic control of drug carriers using systems with open-configurations is essential to enable scaling to the size of in vivo applications. In this study, we demonstrate motion control of paramagnetic microparticles in a low Reynolds number fluid, using a permanent magnet-based robotic system with an open-configuration. The microparticles are controlled in three-dimensional (3D) space using a cylindrical NdFeB magnet that is fixed to the end-effector of a robotic arm. We develop a kinematic map between the position of the microparticles and the configuration of the robotic arm, and use this map as a basis of a closed-loop control system based on the position of the microparticles. Our experimental results show the ability of the robot configuration to control the exerted field gradient on the dipole of the microparticles, and achieve positioning in 3D space with maximum error of 300 µm and 600 µm in the steady-state during setpoint and trajectory tracking, respectively.

Author(s): Khalil, I. S. M. and Alfar, A. and Tabak, A. F. and Klingner, A. and Stramigioli, S. and Sitti, M.
Book Title: 2017 IEEE International Conference on Advanced Intelligent Mechatronics (AIM)
Pages: 1117-1122
Year: 2017
Month: July
Day: 3
Bibtex Type: Conference Paper (inproceedings)
DOI: 10.1109/AIM.2017.8014168
Electronic Archiving: grant_archive

BibTex

@inproceedings{8014168,
  title = {Positioning of drug carriers using permanent magnet-based robotic system in three-dimensional space},
  booktitle = {2017 IEEE International Conference on Advanced Intelligent Mechatronics (AIM)},
  abstract = {Magnetic control of drug carriers using systems with open-configurations is essential to enable scaling to the size of in vivo applications. In this study, we demonstrate motion control of paramagnetic microparticles in a low Reynolds number fluid, using a permanent magnet-based robotic system with an open-configuration. The microparticles are controlled in three-dimensional (3D) space using a cylindrical NdFeB magnet that is fixed to the end-effector of a robotic arm. We develop a kinematic map between the position of the microparticles and the configuration of the robotic arm, and use this map as a basis of a closed-loop control system based on the position of the microparticles. Our experimental results show the ability of the robot configuration to control the exerted field gradient on the dipole of the microparticles, and achieve positioning in 3D space with maximum error of 300 µm and 600 µm in the steady-state during setpoint and trajectory tracking, respectively.},
  pages = {1117-1122},
  month = jul,
  year = {2017},
  slug = {8014168},
  author = {Khalil, I. S. M. and Alfar, A. and Tabak, A. F. and Klingner, A. and Stramigioli, S. and Sitti, M.},
  month_numeric = {7}
}