Article 2018

Multiline balanced SSFP for rapid functional imaging at ultrahigh field

{Purpose The goal of this study is to develop and evaluate a multiline balanced steady-state free-precession (bSSFP) sequence for passband functional MRI at ultrahigh field. Methods Passband bSSFP functional MRI experiments using a visual task were performed on a 9.4 T system with echo trains ranging from one up to seven echoes. We analyze the acquisition efficiency, temporal and thermal signal-to-noise ratio, as well as the observed blood oxygen\textendashlevel-dependent (BOLD) signal changes. Results With increasing repetition time and echo train length, the BOLD-related signal change as well as the thermal and temporal noise were improved. Activation patterns and signal changes were stable and reproducible across subjects. Conclusions We propose a multiline bSSFP for functional BOLD imaging that approaches the speed of echo-planar imaging and that shows an increased BOLD sensitivity compared with single-line bSSFP.}

Author(s): Ehses, P and Scheffler, K
Journal: {Magnetic Resonance in Medicine}
Volume: 79
Number (issue): 2
Pages: 994--1000
Year: 2018
Bibtex Type: Article (article)
DOI: 10.1002/mrm.26761
Electronic Archiving: grant_archive

BibTex

@article{EhsesS2017,
  title = {{Multiline balanced SSFP for rapid functional imaging at ultrahigh field}},
  journal = {{Magnetic Resonance in Medicine}},
  abstract = {{Purpose The goal of this study is to develop and evaluate a multiline balanced steady-state free-precession (bSSFP) sequence for passband functional MRI at ultrahigh field. Methods Passband bSSFP functional MRI experiments using a visual task were performed on a 9.4 T system with echo trains ranging from one up to seven echoes. We analyze the acquisition efficiency, temporal and thermal signal-to-noise ratio, as well as the observed blood oxygen\textendashlevel-dependent (BOLD) signal changes. Results With increasing repetition time and echo train length, the BOLD-related signal change as well as the thermal and temporal noise were improved. Activation patterns and signal changes were stable and reproducible across subjects. Conclusions We propose a multiline bSSFP for functional BOLD imaging that approaches the speed of echo-planar imaging and that shows an increased BOLD sensitivity compared with single-line bSSFP.}},
  volume = {79},
  number = {2},
  pages = {994--1000},
  year = {2018},
  slug = {ehsess2017},
  author = {Ehses, P and Scheffler, K}
}