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Miscellaneous 2018

Optimization of OH-CEST contrast at 3T for clinical application of glucoCEST MRI

{A 3D snapshot CEST sequence is optimized for contrast originating from hydroxyl groups of glucose molecules. Multi-B1-multi-pH measurements allow fitting of exchange rates of four glucose hydroxyl groups, which are then used to optimize pre-saturation parameters in simulation. The optimal protocol gave highly reproducible signals in 6 healthy volunteers, and showed no contrast when tested in a brain tumor patient. This protocol provides a robust baseline for glucose injection studies.}

Author(s): Gandhi, C and Longo, D and Anemone, A and Herz, K and Deshmane, A and Lindig, T and Bender, B and Aime, S and Scheffler, K and Zaiss, M
Book Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Year: 2018
Bibtex Type: Miscellaneous (misc)
Electronic Archiving: grant_archive

BibTex 

@misc{GandhiLAHDLBASZ2018,
  title = {{Optimization of OH-CEST contrast at 3T for clinical application of glucoCEST MRI}},
  booktitle = {{Joint Annual Meeting ISMRM-ESMRMB 2018}},
  abstract = {{A 3D snapshot CEST sequence is optimized for contrast originating from hydroxyl groups of glucose molecules. Multi-B1-multi-pH measurements allow fitting of exchange rates of four glucose hydroxyl groups, which are then used to optimize pre-saturation parameters in simulation. The optimal protocol gave highly reproducible signals in 6 healthy volunteers, and showed no contrast when tested in a brain tumor patient. This protocol provides a robust baseline for glucose injection studies.}},
  year = {2018},
  slug = {gandhilahdlbasz2018},
  author = {Gandhi, C and Longo, D and Anemone, A and Herz, K and Deshmane, A and Lindig, T and Bender, B and Aime, S and Scheffler, K and Zaiss, M}
}