@article{item_3011332,
  title = {{Fast track to the neocortex: A memory engram in the posterior parietal cortex}},
  journal = {{Science}},
  abstract = {{Models of systems memory consolidation postulate a fast-learning hippocampal store and a slowly developing, stable neocortical store. Accordingly, early neocortical contributions to memory are deemed to reflect a hippocampus-driven online reinstatement of encoding activity. In contrast, we found that learning rapidly engenders an enduring memory engram in the human posterior parietal cortex. We assessed microstructural plasticity via diffusion-weighted magnetic resonance imaging as well as functional brain activity in an object-location learning task. We detected neocortical plasticity as early as 1 hour after learning and found that it was learning specific, enabled correct recall, and overlapped with memory-related functional activity. These microstructural changes persisted over 12 hours. Our results suggest that new traces can be rapidly encoded into the parietal cortex, challenging views of a slow-learning neocortex.}},
  volume = {362},
  number = {4618},
  pages = {1045--1048},
  publisher = {American Association for the Advancement of Science},
  address = {Washington, D.C.},
  year = {2018},
  slug = {item_3011332},
  author = {Brodt, S and Gais, S and Beck, J and Erb, M and Scheffler, K and Sch\"onauer, M}
}