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T1 Mapping at 7T Using a Novel Inversion-Recovery Look-Locker 3D-EPI Sequence
{We propose a novel Inversion-Recovery Look-Locker 3D-EPI sequence for rapid T1 mapping. The inherent SNR benefit of a 3D acquisition, segmentation along both phase encode directions and a turbofactor introduced to reduce the number of required inversions can be traded freely for acquisition speed, SNR, resolution and geometric distortions. Aside from quantitative validation, two high-resolution T1 mapping applications are demonstrated at 7T: whole-brain with minimal distortions, and reduced field-of-view with geometric distortions matched to corresponding fMRI data. The results show high T1 accuracy for several turbofactor and flip angle combinations compared to a single-slice inversion-recovery 2D-EPI reference.}
@misc{item_3164692, title = {{T1 Mapping at 7T Using a Novel Inversion-Recovery Look-Locker 3D-EPI Sequence}}, booktitle = {{ISMRM 27th Annual Meeting \& Exhibition}}, abstract = {{We propose a novel Inversion-Recovery Look-Locker 3D-EPI sequence for rapid T1 mapping. The inherent SNR benefit of a 3D acquisition, segmentation along both phase encode directions and a turbofactor introduced to reduce the number of required inversions can be traded freely for acquisition speed, SNR, resolution and geometric distortions. Aside from quantitative validation, two high-resolution T1 mapping applications are demonstrated at 7T: whole-brain with minimal distortions, and reduced field-of-view with geometric distortions matched to corresponding fMRI data. The results show high T1 accuracy for several turbofactor and flip angle combinations compared to a single-slice inversion-recovery 2D-EPI reference.}}, year = {2019}, slug = {item_3164692}, author = {Stirnberg, R and Dong, Y and Bause, J and Ehses, P and St\"ocker, T} }