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Measurement of Pulmonary Perfusion under Expiratory and Inspiratory Breathing Conditions using PCASL-bSSFP Imaging at 1.5 Tesla
{Pseudo-continuous-arterial-spin-labeling (PCASL) has been successfully applied in the lung providing high quality perfusion images. The pulmonary blood flow and the respiratory system interact closely: the intrathoracic pressure has impact on the venous return. Therefore, in this work, we evaluate the effects of intrathoracic pressure on lung perfusion by using PCASL imaging in end-expiratory and end-inspiratory breath-hold. PCASL imaging is able to detect changes of parenchymal lung perfusion caused by alterations of the intrathoracic pressure. Perfusion signal measured under end-inspiratory condition were noticeably reduced as compared to end-expiratory breath-hold. This correlated significantly with measured blood flow volume through the pulmonary trunk.}
@misc{item_3319701, title = {{Measurement of Pulmonary Perfusion under Expiratory and Inspiratory Breathing Conditions using PCASL-bSSFP Imaging at 1.5 Tesla}}, booktitle = {{2021 ISMRM \& SMRT Annual Meeting \& Exhibition (ISMRM 2021)}}, abstract = {{Pseudo-continuous-arterial-spin-labeling (PCASL) has been successfully applied in the lung providing high quality perfusion images. The pulmonary blood flow and the respiratory system interact closely: the intrathoracic pressure has impact on the venous return. Therefore, in this work, we evaluate the effects of intrathoracic pressure on lung perfusion by using PCASL imaging in end-expiratory and end-inspiratory breath-hold. PCASL imaging is able to detect changes of parenchymal lung perfusion caused by alterations of the intrathoracic pressure. Perfusion signal measured under end-inspiratory condition were noticeably reduced as compared to end-expiratory breath-hold. This correlated significantly with measured blood flow volume through the pulmonary trunk.}}, year = {2021}, slug = {item_3319701}, author = {Martirosian, P and Pohmann, R and Schwartz, M and Kuestner, T and Kolb, M and Othman, A and Zhang, C and Scheffler, K and Nikolaou, K and Schick, F and Seith, F} }