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Deuterium Metabolic Imaging of the human brain at 9.4 T: Coil design and dynamic glucose uptake
{DMI (Deuterium Metabolic Imaging) is a technique that enables the investigation of metabolic turnover rates along predefined pathways non-invasively. In this work, we present first DMI data from the human brain at B0 \textequals 9.4T and an investigation of the dynamic glucose uptake in different areas of the human head for healthy volunteers and after the oral administration of [6,6\textquoteright-2H]-glucose. We present a dedicated phased array coil design and 2H MRSI data with high spatial resolution for water, glucose, Glx and lipid/lactate. Finally, we compare the uptake curves for different regions in the human head.}
@misc{item_3319806, title = {{Deuterium Metabolic Imaging of the human brain at 9.4 T: Coil design and dynamic glucose uptake}}, booktitle = {{2021 ISMRM \& SMRT Annual Meeting \& Exhibition (ISMRM 2021)}}, abstract = {{DMI (Deuterium Metabolic Imaging) is a technique that enables the investigation of metabolic turnover rates along predefined pathways non-invasively. In this work, we present first DMI data from the human brain at B0 \textequals 9.4T and an investigation of the dynamic glucose uptake in different areas of the human head for healthy volunteers and after the oral administration of [6,6\textquoteright-2H]-glucose. We present a dedicated phased array coil design and 2H MRSI data with high spatial resolution for water, glucose, Glx and lipid/lactate. Finally, we compare the uptake curves for different regions in the human head.}}, year = {2021}, slug = {item_3319806}, author = {Ruhm, L and Avdievitch, N and Ziegs, T and Nagel, AM and De Feyter, HM and de Graaf, RA and Henning, A} }