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Simulation of 13C Labeling Effects in 1H MRS with different Sequences at 9.4 T
{Glutamate related metabolism can be measured considering the 13C labeling effects from an administered 13C labeled substrate in 1H MR spectra without 13C channels. The advantage of this technique is that some challenges of 13C MRS like non-standard hardware modifications etc. are avoided and the simultaneous observation of 12C- and 13 C-coupled protons is possible. On the other hand the latter also complicates the spectra. In this work, different sequences will be compared to optimize spectral resolution for glutamate and glutamine at 9.4 T.}
@misc{item_3000143, title = {{Simulation of 13C Labeling Effects in 1H MRS with different Sequences at 9.4 T}}, booktitle = {{MRS Workshop 2018 Metabolic Imaging}}, abstract = {{Glutamate related metabolism can be measured considering the 13C labeling effects from an administered 13C labeled substrate in 1H MR spectra without 13C channels. The advantage of this technique is that some challenges of 13C MRS like non-standard hardware modifications etc. are avoided and the simultaneous observation of 12C- and 13 C-coupled protons is possible. On the other hand the latter also complicates the spectra. In this work, different sequences will be compared to optimize spectral resolution for glutamate and glutamine at 9.4 T.}}, year = {2018}, slug = {item_3000143}, author = {Ziegs, T and Henning, A} }