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Correlation between APT-CEST and 18F-Choline PET in glioma at 3T
{Chemical exchange saturation transfer MRI is emerging as a powerful diagnostic tool and has been shown to correlate with glioma tumour grade and molecular genetics. In this study, we aim to investigate whether APT signal is a non-invasive biomarker of Teenage and Young Adult glioma cell proliferation through correlation with 18F-Cho PET SUV as the gold standard. The strong positive correlation found in APT and 18F-Cho PET SUV indirectly demonstrates that APT SI may be a marker of glioma cell proliferation and further demonstrates the potential of APT in the assessment of glioma burden.}
@misc{RegaTHZCAPGDSH2018, title = {{Correlation between APT-CEST and 18F-Choline PET in glioma at 3T}}, booktitle = {{Joint Annual Meeting ISMRM-ESMRMB 2018}}, abstract = {{Chemical exchange saturation transfer MRI is emerging as a powerful diagnostic tool and has been shown to correlate with glioma tumour grade and molecular genetics. In this study, we aim to investigate whether APT signal is a non-invasive biomarker of Teenage and Young Adult glioma cell proliferation through correlation with 18F-Cho PET SUV as the gold standard. The strong positive correlation found in APT and 18F-Cho PET SUV indirectly demonstrates that APT SI may be a marker of glioma cell proliferation and further demonstrates the potential of APT in the assessment of glioma burden.}}, year = {2018}, slug = {regathzcapgdsh2018}, author = {Rega, M and Torrealdea, F and Hearle, J and Zaiss, M and Carvalho, A and Asaf, A and Punwani, S and Golay, X and Dickson, J and Shankar, A and Hyare, H} }