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Research Overview
MRI-powered wireless medical millirobots
Among many medical imaging modalities, magnetic resonance imaging (MRI) at-tracts the most attention with superior image contrast, unlimited imaging depth, and ionizing radiation-free nature. MRI is considered the gold standard in manydiagnostic applications, such as brain tumor and stroke diagnosis, and has alreadyproven itself in guiding medical tools, such as biopsy needles and focus ultra-sound. Besides its high-quality medical imaging, MRI scanners are human-sized electromagnetic systems that could be used for magnetic actuation purposes, whichmakes them a perfect candidate for a combined imaging and actuation platform formagnetic microrobots. Our research focus on developing novel magnetic actuation, MR imaging/sensing methods for medical microrobotic systems.
We have developed various wireless milli- and microrobots powered and tracked using an our 7 Tesla (7T) small-animal MRI scanner. We focused on three main approaches to use MRI’s hardware to actuate wireless robotic systems: magnetic gradient force-based 3D pulling, Ultrahigh field magnetic actuation and Lorentz force-based rotation. Moreover, we also developed fast MRI methods for tracking magnetic robots, deep learning-based microrobot tracking algorithms and localization approaches for micron-scale microrobot aggregates. Later, we combine magnetic microrobots with focus ultrasound system to develop microrobotic on-demand drug delivery. Finally, we investigate new MRI sensing modalities for remote temperature sensing and nanodiamond-based novel contrast agents for microrobotic system in MR images.
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