Enhanced Flexible Mold Lifetime for Roll‐to‐Roll Scaled‐Up Manufacturing of Adhesive Complex Microstructures
Bioinspired Microstructured Adhesives with Facile and Fast Switchability for Part Manipulation in Dry and Wet Conditions
Smart Materials for manipulation and actuation of small-scale structures
3D nanofabrication of various materials for advanced multifunctional microrobots
Liquid Crystal Mesophase of Supercooled Liquid Gallium And Eutectic Gallium–Indium
Machine Learning-Based Pull-off and Shear Optimal Adhesive Microstructures
Information entropy to detect order in self-organizing systems
Individual and collective manipulation of multifunctional bimodal droplets in three dimensions
Microrobot collectives with reconfigurable morphologies and functions
Self-organization in heterogeneous and non-reciprocal regime
Biomimetic Emulsion Systems
Giant Unilamellar Vesicles for Designing Cell-like Microrobots
Bioinspired self-assembled colloidal collectives drifting in three dimensions underwater
In situ sensing physiological properties of biological tissues using wireless miniature soft robots
Implanted electronic sensors, compared with conventional medical imaging, allow monitoring of advanced physiological properties of soft biological tissues continuously, such as adhesion, pH, viscoelasticity, and biomarkers for disease diagnosis. However, they are typically invasive, requiring being deployed by surgery, and frequently cause inflammation. Here we propose a minimally invasive method of using wireless miniature soft robots to in situ sense the physiological properties of tissues. By controlling robot-tissue interaction using external magnetic fields, visualized by medical imaging, we can recover tissue properties precisely from the robot shape and magnetic fields. We demonstrate that the robot can traverse tissues with multimodal locomotion and sense the adhesion, pH, and viscoelasticity on porcine and mice gastrointestinal tissues ex vivo, tracked by x-ray or ultrasound imaging. With the unprecedented capability of sensing tissue physiological properties with minimal invasion and high resolution deep inside our body, this technology can potentially enable critical applications in both basic research and clinical practice.
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