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ProFit-v3: accuracy and precision evaluation of a new spectral fitting software
{In this work, we present the newly developed MRS fitting software ProFit-v3, including adaptive baseline stiffness control and a newly proposed cost function calculation. ProFit-v3 was evaluated for accuracy and precision using both simulated and in vivo spectra, and the results were compared against LCModel. The adaptive spline baseline model of ProFit-v3 modelled different simulated baseline distortions well. The fitting accuracy measured on simulated data was slightly better for ProFit-v3 than for LCModel. While the fitting precision of ProFit-v3 was comparable to that of LCModel for the simulated data, LCModel proved to be somewhat more precise for in vivo spectra.}
@misc{item_3319809, title = {{ProFit-v3: accuracy and precision evaluation of a new spectral fitting software}}, booktitle = {{2021 ISMRM \& SMRT Annual Meeting \& Exhibition (ISMRM 2021)}}, abstract = {{In this work, we present the newly developed MRS fitting software ProFit-v3, including adaptive baseline stiffness control and a newly proposed cost function calculation. ProFit-v3 was evaluated for accuracy and precision using both simulated and in vivo spectra, and the results were compared against LCModel. The adaptive spline baseline model of ProFit-v3 modelled different simulated baseline distortions well. The fitting accuracy measured on simulated data was slightly better for ProFit-v3 than for LCModel. While the fitting precision of ProFit-v3 was comparable to that of LCModel for the simulated data, LCModel proved to be somewhat more precise for in vivo spectra.}}, year = {2021}, slug = {item_3319809}, author = {Borbath, T and Murali-Manohar, S and Dorst, J and Wright, AM and Henning, A} }