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Multicolor metabolic quantitative CEST (mmqCEST): high resolution imaging of brain metabolites
{The relatively low spatial resolution (ca. 250 mm3) of 1H-MRS hinders its application towards probing heterogeneous diseased tissue, e.g. tumor tissue. Therefore, we present mmqCEST, a metabolic imaging technique based on the saturation transfer from RF-tagged metabolites to the bulk water [1]. mmqCEST decodes a frequency-dependent metabolite-weighted contrast in the Z-spectra into (multicolor) quantitative metabolic maps with a high spatial resolution (ca. 3.4 mm3).}
@misc{item_3038375, title = {{Multicolor metabolic quantitative CEST (mmqCEST): high resolution imaging of brain metabolites}}, booktitle = {{7th International Workshop on Chemical Exchange Saturation Transfer (CEST 2018)}}, abstract = {{The relatively low spatial resolution (ca. 250 mm3) of 1H-MRS hinders its application towards probing heterogeneous diseased tissue, e.g. tumor tissue. Therefore, we present mmqCEST, a metabolic imaging technique based on the saturation transfer from RF-tagged metabolites to the bulk water [1]. mmqCEST decodes a frequency-dependent metabolite-weighted contrast in the Z-spectra into (multicolor) quantitative metabolic maps with a high spatial resolution (ca. 3.4 mm3).}}, pages = {19}, year = {2018}, slug = {item_3038375}, author = {Khlebnikov, V and Bhogal, A and Schuppert, M and Zaiss, M and Lindig, T and Bender, B and Ernemann, U and Scheffler, K and Luijten, P and Hoogduin, H and Klomp, D and Prompers, J} }