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Fat corrected APT-CEST in the human breast
{CEST in the mammary gland is affected by lipid signals1-5 not only causing strong pseudo rNOE artifacts4, but also leading to an incorrect normalization of the Z-spectrum in the spectral region of the amide proton transfer (APT) signal. Here, we propose to approximate the total fat signal by the residual magnetization at $\Delta$$\omega$ \textequals 0 ppm. This enables the correction of Z-spectra for fat signal induced artifacts without any additional measurements and thus fat independent quantitative APT-CEST imaging.}
@misc{item_3038385, title = {{Fat corrected APT-CEST in the human breast}}, booktitle = {{7th International Workshop on Chemical Exchange Saturation Transfer (CEST 2018)}}, abstract = {{CEST in the mammary gland is affected by lipid signals1-5 not only causing strong pseudo rNOE artifacts4, but also leading to an incorrect normalization of the Z-spectrum in the spectral region of the amide proton transfer (APT) signal. Here, we propose to approximate the total fat signal by the residual magnetization at $\Delta$$\omega$ \textequals 0 ppm. This enables the correction of Z-spectra for fat signal induced artifacts without any additional measurements and thus fat independent quantitative APT-CEST imaging.}}, pages = {73}, year = {2018}, slug = {item_3038385}, author = {Zimmermann, F and Korzowski, A and Schuenke, P and Breitling, J and Zaiss, M and Paech, D and Ladd, ME and Bachert, P and Goerke, S} }